Isotopically Labeled Compounds
Medchemexpress LLC L-Leucine-d10 | 106972-44-5 | 141.23 | 5 MG
L-Leucine-d10 is a deuterium-labeled L-Leucine, an essential branched-chain amino acid (BCAA) that activates the mTOR signaling pathway. This compound is intended for research use only and can serve as a tracer or an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Deuteration, which incorporates stable heavy isotopes, is recognized for its potential to influence the pharmacokinetic and metabolic profiles of drugs, making L-Leucine-d10 valuable in drug development processes.
- Deuterium labeled L-Leucine
- Essential branched-chain amino acid
- Activates the mTOR signaling pathway
- For research use only
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC DL-Aspartic acid-d3 | 14341-75-4 | MFCD00144167 | 136.12 | 5 MG
DL-Aspartic acid-d3 is a deuterium labeled L-Aspartic acid. L-Aspartic acid is an amino acid capable of penetrating the blood-brain barrier. It is often utilized in the preparation of prodrugs designed to target colon and cecal tissues, and is commonly used in studies of inflammatory conditions.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC L-Tyrosine-d2 | 72963-27-0 | 183.20 | 100 MG
L-Tyrosine-d2 is the deuterium labeled L-Tyrosine, a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of hydrogen and carbon into drug molecules for quantitation during drug development.
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories Di-N-Butyl phthalate (ring-D4 98%) 100 ug/mL in nonane 1 2 mL
Di-N-Butyl phthalate (ring-D4 98%) 100 ug/mL in nonane 1 2 mL
Medchemexpress LLC Acetylcholine-d4 (bromide) | 93449-31-1 | 98.0% | 10 MG
Acetylcholine-d4 (bromide) is the deuterium-labeled analogue of acetylcholine bromide supplied for research and analytical use. It serves as an isotopically labeled tracer and internal standard for quantitative assays and is provided as a high-purity solid suitable for spectroscopic and mass-spectrometric workflows.
- isotopically labeled internal standard for quantitative analysis
- compatible with NMR, GC-MS, and LC-MS workflows
- high chemical purity (98.0%) for reliable quantitation
- solid, white to off-white appearance for ease of handling
- stable when stored sealed and protected from moisture; in solvent: -80°C (up to 6 months) or -20°C (up to 1 month)
- intended for research use only
Cambridge Isotope Laboratories L-PHENYLALANINE (3,3-D2, 98%), 0.5 G
L-PHENYLALANINE (3,3-D2, 98%), 0.5 G
Medchemexpress LLC Rofecoxib-d5 | 544684-93-7 | 319.39 | 500 UG
Rofecoxib-d5 is a deuterium-labeled variant of Rofecoxib, a potent and orally active COX-2 inhibitor. It exhibits high selectivity for COX-2 over human COX-1, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, respectively, and an over 1000-fold selectivity for COX-2 compared to human COX-1 in U937 cells and Chinese hamster ovary cells.
- Can be utilized as a tracer in various applications.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes like deuterium can influence the pharmacokinetic and metabolic profiles of compounds.
Cambridge Isotope Laboratories 2-Hydroxyethyl bis(2-butoxyethyl)phosphate (D4 97%) 100 ug/mL in acetonitrile 1 2 mL
2-Hydroxyethyl bis(2-butoxyethyl)phosphate (D4 97%) 100 ug/mL in acetonitrile 1 2 mL
Cambridge Isotope Laboratories Bis(2-chloroethyl)phosphate (D8 97%) 100 ug/mL in acetonitrile 1 2 mL
Bis(2-chloroethyl)phosphate (D8 97%) 100 ug/mL in acetonitrile 1 2 mL
Cambridge Isotope Laboratories Corticosterone (9 11 12 12-D4 98%) 5 mg
Corticosterone (9 11 12 12-D4 98%) 5 mg
Cambridge Isotope Laboratories Terephthalic acid (ring-D4 98%) 1 g
Terephthalic acid (ring-D4 98%) 1 g
Medchemexpress LLC Adipic acid-d10 | 25373-21-1 | MFCD00190459 | 99.9% | 156.20 g/mol | C6D10O4 | 10 MG
Adipic acid-d10 (hexanedioic acid-d10) is the deuterated isotopologue of adipic acid used as a tracer and internal standard for quantitative analytical workflows. Supplied as a high-purity powder, it is intended for research applications requiring mass or NMR differentiation and includes recommended storage conditions for powder and solutions.
- High isotopic labeling enables clear mass spectrometric distinction.
- Purity 99.93% supports accurate quantitation.
- Suitable as a tracer and internal standard for NMR, GC-MS, and LC-MS.
- Available in small reference pack sizes for analytical use.
- Powder and solvent storage recommendations help preserve stability.
